Juvenile xanthogranuloma - Xanthogranuloma Yolutsha
☆ Kwiziphumo zika-2022 ze-Stiftung Warentest ezivela eJamani, ukwaneliseka kwabathengi ngeModelDerm bekungaphantsi kancinci kunokubonisana nge-telemedicine ehlawulweyo.
References
Juvenile xanthogranuloma (JXG) yimeko eqhelekileyo kwaye lolona hlobo luxhaphakileyo lwe non-Langerhans cell histiocytic disorder ebantwaneni. Malunga ne-75% yeemeko, ezi zilonda zivela kunyaka wokuqala wobomi, kwaye ngaphezu kwe-15-20% yezigulane banazo ukususela ekuzalweni. Nangona inqabileyo kubantu abadala, i-JXG idla ngokuphindaphindiweyo kubantu abaneminyaka engamashumi amabini ukuya kweyesithathu, kwaye izigulane ezininzi zabantu abadala zinezilonda esinye. Ngokweklinikhi, kubonakala njengamaqhuqhuva aqinileyo okanye amaqhuma aqinileyo omnye okanye omthubi-orenji-brown, ngakumbi ebusweni, entanyeni, nangaphezulu komzimba. Izilonda zomlomo aziqhelekanga kodwa zinokubonakala njengegaqa elityheli emacaleni olwimi okanye kwenye indawo emlonyeni, mhlawumbi okukhokelela kwizilonda nokopha. Izilonda zolusu azibangeli zimpawu kwaye zidla ngokuzihambela ngokwazo kwiminyaka emininzi. Nangona kunqabile, ukubandakanyeka kwe-ocular ngowona mcimbi uxhaphakileyo ngaphaya kwesikhumba, ulandelwa kukubandakanyeka kwemiphunga. Ocular JXG ichaphazela iliso elinye kuphela kwaye yenzeke ngaphantsi kwe- 0. 5 % yezigulane, nangona malunga ne-40% yabo babandakanyeka kwi-ocular nabo banezilonda ezininzi zolusu xa zifunyaniswa.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) aziqhelekanga, izifo ezinobungozi eziyinxalenye yodidi olukhulu lwe non-Langerhans cell histiocytoses. Ngokuqhelekileyo zivela njengeqhuma elinye okanye ezininzi ezibomvu okanye ezityheli, zihlala zifumaneka entloko okanye entanyeni. Uninzi lwe-JXGs luphuhla mhlawumbi ekuzalweni okanye kunyaka wokuqala wobomi. Nangona kungaqhelekanga, ngamanye amaxesha banokuchaphazela iindawo ezingaphaya kwesikhumba, kunye nokubandakanyeka kwamehlo kuba yinto yokubukela ngokutsho koncwadi olukhoyo. Ngokubanzi, ii-JXGs eluswini zihamba zodwa kwaye azifuni nyango.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
I-ocular lesion ibonakalisa ukuya kwi-10% yabantu abane-JXG kwaye inokuchaphazela umbono wabo. Nangona izilonda ezikwisikhumba zidla ngokunyamalala ngokuzenzekelayo, izilonda zamehlo azifane ziphucuke ngokuzenzekelayo kwaye zifuna unyango.